Magneto-Nano Chips for Ultrasensitive and Multiplex Detection of Protein Biomarkers of Tumor

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户:cyc528528
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  Reproducible and multiplex protein assays are greatly desired by cancer biologists as well as clinical oncologists to rapidly follow numerous proteins in clinical samples.We have now successfully applied magneto-nano bioehips based on giant magnetoresistance (GMR) spin valve sensor arrays and magnetic nanoparticle labels (nanotags) to the detection of biological events in the form of multiplex protein assays (4-to 64-plex) with great speed (0.5-2 hours), sensitivity (1 picogram/ml concentration levels or below), selectivity, and economy [1].The technology platform is well suited for longitudinal studies of animal or human cohorts after therapeutic intervention or radiation exposure [2].
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