The impact of up-regulated microglial cathepsin H on LPS-induced neuro inflammation

来源 :The 18th Congress of the International Federation of Associa | 被引量 : 0次 | 上传用户：lrq22

【摘要】

：

Microglia-derived proteases play important roles in inflammation.However, Cathepsin H (Cat H), a cysteine protease, has been far less studied in neuroinflammation.This study aims at the changes and ro

【作者】

：

Kai Fan Yanli Zhang Junjie Liang Changyi Hou Hongliang Xiao Jianmei Ma

【机构】

：

Department of Anatomy, Dalian Medical University, Dalian 116044, China

【出处】

：

The 18th Congress of the International Federation of Associa

【发表日期】

：

2014年8期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

The expression of monocyte chemoattactant protein-1 in amygdala of mice with chronic inflammatory pa

To observe the expression and cellular distribution of monocyte chemoattractant protein-l(MCP-1) and CCR2 in amygdala following complete Freunds adjuvant (CFA) induced chronic inflammatory pain.①Mecha

会议

Different responses of galanin and calcitonin gene-related peptide to capsaicin stimulation on dorsa

Both galanin (Gal) and calcitonin gene-related peptide (CGRP) are sensory neuropeptides which expressed in dorsal root ganglion (DRG) neurons and are involved in nociceptive processing.Capsaicin (CAP)

会议

Aβ-Stimulated BMDCs combined with spleen-derived cells attenuates learning and memory deficits and p

Anti-Aβ immunotherapy could reduce amyloid plaques and amyloid-associated pathologies, attenuate learning and memory deficits in AD animal models.Immune senescence has been proved to play a crucial ro

会议

Influence of the astragalus injection on perihematomal mitochondrial Mn-SOD and Cyt-c expression in

To observe Astragalus injection on perihematomal mitochondrial manganese superoxide dismutase (Mn-SOD) and cytochrome C (Cyt-c) in rats.SD rats were randomly divided into four groups, namely the norma

会议

The association of single nucleotide polymorphisms of ALOX5 gene with its gene expression and IgE sy

The leukotrienes constitute a group of arachidonic acidderived compounds with biologic activities suggesting important roles in inflammation and immediate hypersensitivity, especially in the case of a

会议

PIGF protects cortical neurons in vitro from cerebral ischemia injury by activation of ERK 1/2 and i

Placental growth factor (PIGF) has been demonstrated to express in CNS and involve in cerebral ischemia injury.Our study explored the mechanisms about the neuroprotective effects of PIGF on cortical n

会议

Sulforaphane protects rodent retinas against ischemia-reperfusion injury through activation of the N

Retinal ischemia-reperfusion (I/R) injury is associated with many ocular diseases.Sulforaphane (SF) has cytoprotective effects against oxidative stress.This study was undertaken to determine whether S

会议

Changes of advanced glycation end-product expression in the gastrointestinal tract of type 2 diabeti

To investigate the levels of advanced glycation of end-products (AGEs) and their receptor (RAGE) expression in the gastrointestinal (GI) tract in type 2 diabetic rats.GK diabetic rats and age-matched

会议

Expression of protein-disulfide isomerase-associated 3 in pancreas and liver of diet-induced obesity

The chronic disease which caused by obesity has serious risk in the developed world.Obesity induced endoplasmic reticulum (ER) stress is resulted from the accumulation of misfolded proteins during str

会议

The effects of sedum lineare thunb alcohol extracton on NF-κB and cytokine in S180-bearing mice

Our previous study shows that Sedum Lineare Thunb (SLT) alcohol extract has antitumor effect on S180 bearing-mice.However, the mechanism has been unknown.Our aims are to explore if its effect is throu

会议

The impact of up-regulated microglial cathepsin H on LPS-induced neuro inflammation

与本文相关的学术论文