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5. Inhibition of human ether à go-go (hEAG1) potassium channel by Phosphatidylinositol-4,5-bisphosphate

Inhibition of human ether à go-go (hEAG1) potassium channel by Phosphatidylinositol-4,5-bisphosphate

来源 :The 10th Chinese Symposium on Calcium Signaling(第十届全国钙信号和细胞功 | 被引量 : 0次 | 上传用户：Aegean1218

【摘 要】

：

Human ether à go-go (hEAG) channels are important for tumor development and have been recognized as a potential therapeutic target.However, the knowledge of hE

【作 者】

：

Bo Han Man Zhang Linli Yang Yin Tang Chunlin Cai Ling Bai Kunyan He Shangwei Hou 

【机 构】

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KeyLaboratoryofSystemsBiomedicine(MinistryofEducation),ShanghaiJiaoTongUniversity,Shanghai,200240,Ch

【出 处】

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The 10th Chinese Symposium on Calcium Signaling(第十届全国钙信号和细胞功

【发表日期】

：

2014年7期

【关键词】

：

hEAG1 potassium channel PIP2 biomolecular interactions patch clamp 

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Human ether à go-go (hEAG) channels are important for tumor development and have been recognized as a potential therapeutic target.However, the knowledge of hEAG channel regulation is very limited.We show here that hEAG1 channel can be regulated by Phosphatidylinositol-4,5-bisphosphate (PIP2).

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