Protein phosphorylation regulates amino-acid-induced mTORC 1 signaling and cell growth

来源 :第十一届全国酶学学术讨论会暨邹承鲁诞辰90周年纪念会 | 被引量 : 0次 | 上传用户:jeffzhangjf
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Abstract: Protein phosphorylation is the most widespread type of post-translational modification used in signal transduction.It can be achieved through the phosphorylation of proteins that control the levels of second messengers, through the phosphorylation of protein kinases and phosphatases themselves, or through the reversible phosphorylation of their substrates.Thus, it affects every basic cellular process, including metabolism, growth, division, differentiation, motility, organelle trafficking, membrane transport, muscle contraction, immunity, learning and memory.
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