论文部分内容阅读
蛋白质或者脂类分子经过糖链修饰后形成糖蛋白或糖脂。糖链的半乳糖具有3羟基结构，我们的研究发现糖链半乳糖的3O硫酸酯修饰可以形成一种特殊结构单元，我们称之为半乳糖硫酸酯结构单位。这种特殊的结构单元见于人体组织中的重要分子中，其调节功能和活性作用正受到重视。
半乳糖硫酸酯结构单位的功能研究
【摘 要】
：
蛋白质或者脂类分子经过糖链修饰后形成糖蛋白或糖脂。糖链的半乳糖具有3羟基结构，我们的研究发现糖链半乳糖的3O硫酸酯修饰可以形成一种特殊结构单元，我们称之为半乳糖硫酸酯结构单位。这种特殊的结构单元见于人体组织中的重要分子中，其调节功能和活性作用正受到重视。
【机 构】
：
复旦大学上海医学院生物化学与分子生物学系,上海200032
【出 处】
：
中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议
【发表日期】
：
2018年10期
其他文献
ATP-dependent Lon protease is a nuclear DNA-encoded mitochondrial enzyme highly conserved throughout evolution,contributed to the degradation of abnormal proteins within mitochondrial matrix,in the co
Stimulation of innate immune processes represents an attractive strategy to achieve multiple therapeutic outcomes including inhibition of virus replication,boosting antitumor immunity,enhancing vaccin
10-Hydroxycamptothecin(HCPT),a natural camptothecin(CPT)analog that is more potent anti-cancer activity,was widely used in recent clinical trials.Autophagy is becoming recognized as an important biolo
With an aging society in the speed,improvement of the physical function status and quality of life is more meaningful than a longer-living in the elderly.Previous studies have shown that a recombinant
Antioxidant Peptide Purified from Enzymatic Hydrolysates of Isochrysis Zhanjiangensis and its Protec
Marine microalgae have been widely applied in cosmaceuticals,nutraceuticals,and functional foods.In the present study,we first investigated the hepatoprotective effects of peptide purified from microa
Chiral sulfoxides are valuable organosulfur compounds and have been widely used as important intermediates in asymmetric synthesis and as bioactive ingredients in pharmaceutical industry.Asymmetric bi
Roles of N-terminal Asparagine Amidohydrolase Gene from Apis cerana cerana in Oxidative Stress Respo
N-terminal asparagine amidohydrolase(Ntan1)is a feature of the ubiquitin-dependent N-end rule pathway of protein degradation which has been implicated in a legion of physiological functions: sensing o
Bacterial persister is a sub-group of special population of bacteria,and has the distinction marks from the ordinary bacteria and resistant mutants.The presence of persister is believed to be closely