Molecular simulation assisted identification of Ca2+ binding residues in TMEM16A

来源 :第二届全国计算生物学与生物信息学学术会议 | 被引量 : 0次 | 上传用户:AJ0704
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Background:Calcium-activated chloride channels(CaCCs)are dual regulated by intracellular calcium and membrane voltage and play vital roles in a variety of physiological processes.
其他文献
  microRNA(miRNA)在后生动物、植物细胞分化、生长发育、正常生理功能的维持、疾病的发生、发展和转归中发挥重要功能。通常人们认为已知miRNA对应的序列就是存储于miRBas
  脆性X智力障碍1基因(fragile X mental retardation 1 gene,FMR1)是脆性X综合征的致病基因。以往研究表明,该基因存在复杂的可变剪接表达。而可变剪接对FMR1基因功能的影
  植物Na+,K+/H+反向转运蛋白是H+偶联的反向离子转运蛋白,在细胞离子平衡方面起着重要作用。荒漠抗逆植物胡杨含有6个Na+,K+/H+反向转运蛋白基因(PeNHX1-6),其耐盐胁迫功
  Cancer is a highly heterogeneous disease of the uncontrolled proliferating cells,suffering from extensive genetic and epigenetic defects and displaying supe
  在哺乳动物体细胞内,大量基因被基因组修饰所关闭,但对DNA进行甲基化的DNMT和对染色质进行修饰的PRC蛋白缺乏识别特定基因组位点的能力。大量证据提示,许多lncRNA既包含DNA
会议
  Background: As one of the most important and ubiquitous post-translational modifications(PTMs),the reversible protein phosphorylation plays a crucial role i
会议
  Background: To analytically model gene expression is a general interest and has be discussed for decades.However,there still lack an efficient and assumptio
  HIV-1-neutralizing antibodies develop in most HIV-1-infected individuals,although highly effective anti-bodies are generally observed only after years of ch
会议
  Large-scale cancer genomics projects are providing a large volume of data about genomic,epigenomic,and gene expression aberrations in multiple cancer types.
会议
  结核病(tuberculosis,TB)危害人类健康已有数千年之久,曾被称为人类的瘟疫。卡介苗(BCG),是目前世界上唯一获准用于预防结核病的疫苗,于1921年由法国科学家卡尔梅特(Calm
会议