Cancer is a highly heterogeneous disease of the uncontrolled proliferating cells,suffering from extensive genetic and epigenetic defects and displaying supe
Background: As one of the most important and ubiquitous post-translational modifications(PTMs),the reversible protein phosphorylation plays a crucial role i
Background: To analytically model gene expression is a general interest and has be discussed for decades.However,there still lack an efficient and assumptio
HIV-1-neutralizing antibodies develop in most HIV-1-infected individuals,although highly effective anti-bodies are generally observed only after years of ch
Large-scale cancer genomics projects are providing a large volume of data about genomic,epigenomic,and gene expression aberrations in multiple cancer types.