【摘 要】
：
Since being introduced by Schmalz et al,1 alkynylcyclopropane(ACP)ketone has recently been proved to be a versatile building block in organic synthesis.As a
【机 构】
：
State Key Laboratory and Institute of Elemento-Organic Chemistry,Collaborative Innovation Center of
【出 处】
：
中国化学会全国第十二届有机合成化学学术研讨会
论文部分内容阅读
Since being introduced by Schmalz et al,1 alkynylcyclopropane(ACP)ketone has recently been proved to be a versatile building block in organic synthesis.As a novel type of donor-acceptor cyclopropane,ACP ketone has also got attractive attentions in recent years for its novel types of cycloaddition.2,3 In these cycloadditions,ACP ketones were mostly used as 1,4-dipoles2 and the examples of ACP ketones as 1,3-dipoles3 were quite limited.Herein,we report a Lewis acid-catalyzed intermolecular [3+2] cycloaddition of ACP ketones with electron-rich aromatic aldehydes,by which 2,5-trans-tetrahydrofurans were constructed diastereoselectively.
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