Ga(OTf)3 Catalyzed Highly Efficient Substitution Reaction of 3-Hydroxyoxindoles Using TMSN3

来源 :中国化学会全国第十二届有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户：zhuxh054

【摘要】

：

　　We report a highly efficient substitution reaction of 3-hydroxyoxindoles 1 using TMSN3 to furnish 3-substituted 3-azidooxindoles as the precursor of quatern

【作者】

：

YinXiao-Ping;ZhouJian;

【机构】

：

Shanghai Key Laboratory of Green Chemistry and Chemical Processes,School of Chemistry and Molecular

【出处】

：

中国化学会全国第十二届有机合成化学学术研讨会

【发表日期】

：

2015年期

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　　We report a highly efficient substitution reaction of 3-hydroxyoxindoles 1 using TMSN3 to furnish 3-substituted 3-azidooxindoles as the precursor of quaternary 3-aminooxindoles.Under the condition of using Ga(OTf)3 as the Lewis acid catalyst and acetonitrile as the solvent,a variety of differently substituted 3-aryl 3-hydroxyoxindoles work well with TMSN3 to provide the corresponding 3-aryl 3-azidooxindoles in good to excellent yield.

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Ga(OTf)3 Catalyzed Highly Efficient Substitution Reaction of 3-Hydroxyoxindoles Using TMSN3

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