中药有效成分莫诺苷对血小板聚集钙离子的影响

来源 :第四届中国药理学会补益药药理专业委员会学术研讨会 | 被引量 : 0次 | 上传用户:mdjsh123
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目的 研究莫诺苷对二磷酸腺苷(ADP)诱导兔血小板聚集后Ca2+浓度的影响.方法 利用Fura-2/AM荧光法,通过记录5min之内Fura-2在激发波长340nm和380nm处的荧光强度比值检测不同条件下ADP诱导血小板聚集后Ca2+的变化.结果 与空白对照组相比,莫诺苷能显著抑制由ADP诱导兔血小板聚集后Ca2+的升高(P<0.001).
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