Epileptogenesis in Human Gelastic Seizures with Hypothalamic Hamartoma

来源 :2011第二届国际神经科技大会 | 被引量 : 0次 | 上传用户:susan002
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Human hypothalamic hamartoma (HH) is a developmental malformation often characterized by gelastic seizures that are refractory to anti-epileptic drugs.The only effective control of gelastic seizures is the surgical treatment.HH is intrinsically epileptogenic, but the mechanisms of seizure genesis operative within this subcortical lesion are unknown.Since 2003, Barrow Neurological Institute (BNI) has been developing a multidisciplinary clinical program to evaluate, diagnose, treat, counsel patients and families and study epileptogenic mechanisms with this disorder.
其他文献
BACKGROUND AND PURPOSE: dowuregulation of the tumor suppressor, phosphatase and (tla)sin homolog deleted on chromosome 10 (PTEN), is thought to be a novel neuroprotective strategy in ischemic stroke,b
会议
Atherosclerosis is a devastating chronic inflammatory disease, which results in intimal expansion of the large arteries, plaque formation, thrombosis and stroke or myocardial infarction.In advanced at
会议
Symptomatic intracerebral hemorrhage (ICH) is the most dangerous adverse effect of tissue plasminogen activator (tPA), the only FDA-approved drug, for treating acute ischemic stroke patients.Currently
会议
It is well known that gender differences exist in risk and outcome of ischemic stroke.In addition, surgical menopause (long term ovariectomy) is associated with an increased risk of Alzheimers disease
会议
Stroke is caused by the sudden onset of loss of neurological functions because of the blood flow to the brain has been cut off which leads to cerebral ischemia.Axonal damage, neuronal loss and regener
会议
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive method of stimulating the brain that changes excitability at the site of stimulation as well as at distant anatomically connected
会议
Minimally invasive procedures for evacuation of intracerebral hematoma have been demonstrated to be a promising method, patients underwent minimally invasive procedures usually have a good recovery of
会议
Introduction: Clevidipine, a rapidly-acting, vascular-selective, L-type dihydropyridine calcium channel blocker, lowers blood pressure (BP) by reducing systemic vascular resistance and has a pharmacok
会议
Over the past two decades, substantial advances in the endovascular management ofischemic cerebrovascular disease have occurred, albeit in a somewhat chaotic and fitful progression, largely as a conse
会议
In recent years use of antipsychotics was widely debated for concerns about their safety in elderly patients affected with dementia.The aim of the present study was to make an update on the use of ant
会议