Identification of Novel PPARα/γ Dual Agonists by Virtual Screening of Specs Database

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：zhi911

【摘要】

：

The thiazolidinedione class PPARγ agonists as antidiabetic agents are restricted in clinical use because of the side effects such as edema,weight gain and heart failure.

【作者】

：

Jun ZHANG Xian-Chao CHENG Run-Ling WANG

【机构】

：

Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics

【出处】

：

2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

：

2015年3期

【关键词】

：

PPARs molecular docking ADMET MD simulation specs database

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　　The thiazolidinedione class PPARγ agonists as antidiabetic agents are restricted in clinical use because of the side effects such as edema,weight gain and heart failure.

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Identification of Novel PPARα/γ Dual Agonists by Virtual Screening of Specs Database

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