论文部分内容阅读
Recently, micro fluidic systems are downscaling to 101-103 nm scale fluidic systems which we call extended nanospace.Due to the transient region from single molecules to normal liquid, many unique liquid properties were reported.In addition, unique applications can be expected.Especially, extended nanospace can provide highly efficient and ultra-small volume separation (chromatography) due to the well-defined small space.However, there are many technical challenges: especially, ultrasensitive detection technology for nonfluorescent molecules.