Objective: To observe the effect of chlorogenic acid extract of Folium Eucommiae (CAEF) and its main components: chlorogenic acid, quercetin and geniposide combined with crocin (C+C+G+Q) on the expres
Our previous studies have proved that epalrestat is able to ameliorate bleomycin-induced pulmonary fibrosis by inhibiting expression of AR.However whether epalrestat attenuates pulmonary vascular remo
Mitochondria are dynamic organelles and continuously undergo fission and fusion processes.Mitochondrial fission is involved in multiple physiological or pathological processes, but the role of mitocho
Objectives: Cardiotoxicity has raised more concerns when using anti-arrhythmia drugs.One of the challenges in the drug development and safety control is the lack of robust and reliable predictive drug
Pathological cardiac hypertrophy is associated with nearly all forms of heart failure.It develops in response to disorders such as coronary artery disease, hypertension, and myocardial infarction.Angi
Atherosclerosis is a chronic multifactorial inflammatory disease with high prevalence worldwide, and has become the leading cause of death.The present study was designed to investigate the impact of h
考察苏格木勒-3汤对异丙肾上腺素所致大鼠心肌肥厚的保护作用并探讨其机制.皮下注射大剂量异丙肾上腺素致大鼠心肌肥厚模型,以苏格木勒-3汤灌胃给药,观察大鼠心脏外观、心脏指数;光镜观察心脏组织形态学变化,用分光光度法及实时定量PCR检测Caspase-3/9的活性和表达情况.与正常对照组相比,异丙肾上腺素处理组心脏变大,缺血,心脏指数升高,病理损伤严重,苏格木勒-3汤改善心脏形态及心脏组织病理变化,降
OBJECTIVE: Refractory wound is a dreaded complication of diabetes and is highly correlated with endothelial precursor cell (EPC) dysfunction caused by hyperglycemia.Acarbose is a widely used oral gluc
OBJECTIVE.Coronary heart disease (CHD) has been the leading cause of death around the world for the past decades.Aspirin (ASA) has established efficacy for preventing cardiovascular events and is pres
目前,心脑血管疾病是全世界死亡率最高的疾病之一,且发病率正呈现上升趋势.传统中药用于防治心脑血管疾病积累了丰富的临床经验.丹参是著名的活血化瘀中药,其主要成分包括酚酸类和丹参酮类.丹参酮类是一类脂溶性萜醌类天然产物,其中的丹参酮ⅡA衍生物-丹参酮ⅡA磺酸钠已经广泛应用于临床.越来越多的研究显示,丹参酮类抗动脉粥样硬化、抗心律失常、抗高血压以及抗缺血再灌注等方面作用显著.本文将对丹参酮类的防治心脑血