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CD29 is the integrin betal subunit.Integrin family members are membrane receptors involved in cell adhesion and recogmtion in a variety of processes including embryogenesis, tissue repair and immune response.In this study, a novel CD29-like gene (LCD29) was identified and characterized in Japanese lamprey (Lethenteron japonicum), an agnathan that occupies a critical phylogenic position between cephalochordates and gnathostomes.