Icariin Ⅱ attenuates myocardial fibrosis by down-regulating TGF-β1/Smad2 signaling pathway in sponta

来源 :2016年全国抗炎免疫药理学术会议 | 被引量 : 0次 | 上传用户:liongliong583
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Objective: To investigate the effects of icariin Ⅱ (IRS) on myocardial fibrosis in spontaneously hypertensive rats (SHR), and to explore the mechanisms.Methods: 14-week-old male SHRs were randomly divided into model group, low, middle and high dose of IRS treatment groups (4, 8, 16 mg/ kg), the same age WKY as negative control group.
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