【摘 要】
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Nature has constructed complicated living systems that often have elaborate hierarchical structure assemblies arising from weakly interacting,yet readily available building blocks.[1] Constructing an
【机 构】
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Molecular Sciences and Biomedicine Laboratory,Hunan University,Changsha,410082
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Nature has constructed complicated living systems that often have elaborate hierarchical structure assemblies arising from weakly interacting,yet readily available building blocks.[1] Constructing an intelligent system that rival the structure and function of living organisms has attracted considerable research interest in self-assembly and bionic science.[2] Photosynthetic bacteria can absorb photons on the submicron scale and efficiently convert light energy into accessible chemical energy.The photosynthetic bacteria-inspired studies can help researchers improve the ability to precisely manipulate photons and develop more efficient energy transfer pathways.[3,4] Herein,we designed artificial photoresponsive protocells that mimic the structure and light-harvesting function of photosynthetic bacteria for imaging-guided photodynamic and photothermal therapy.With the specific structure and function,the protocells can efficiently absorb light strongly as well as convert light energy into chemical and heat energy for ablating tumor cells and suppressing the growth of solid tumor.In summary,our demonstration of protocells not only represents a method for fabricating light-harvesting systems based on nanoassembly,but also provides a promising step towards photosynthetic protocells with integrated cell-like structure and light-harvesting function for nanomedicine.
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