Recent clinical evidence has demonstrated that immunotherapy is a powerful therapeutic strategy for cancer.However,the immune suppressive and tolerant tumor microenvironment (TME) posts immense challe
The translocator protein (TSPO) may impact inflammatory and immune responses.However, the exact actions of TSPO on Th1 cell responses in vitro and in vivo are still unclear.In the current study, we fo
RATIONALE: Idiopathic pulmonary fibrosis (IPF) is a highly heterogeneous and lethal pathological process with limited therapcutic options, which is the most common and severe of the idiopathic interst
Inflammasomes promotes the maturation of interleukin 1β (IL-1β) and IL-18 and triggers pyroptosis.Caspase-1 and-11 (or -4/5 in human) in the canonical and non-canonical inflammasome pathways respectiv
Introduction: To study the reconstitution and clinical significance of T cells subsets of patients undergoing related HLA-haploidentical non T-cell depleted in vitro peripheral blood hematopoietic ste