【摘 要】
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The Nobel Prize 2011 went to Jules Hoffman and Bruce Beutler for their discoveries of Toll-like receptors (TLRs),while Albert Lasker Award for Basic Medical Research 2008 honored the discovery of micr
【机 构】
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Department of Radiation Medicine,Faculty of Naval Medicine,Second Military Medical University,Xiangy
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The Nobel Prize 2011 went to Jules Hoffman and Bruce Beutler for their discoveries of Toll-like receptors (TLRs),while Albert Lasker Award for Basic Medical Research 2008 honored the discovery of microRNA (miRNA),indicating the importance of TLRs and miRNAs.TLRs are the main sentinels of many types of immune cells and they play critical roles in innate and acquired immunity.Dysregulation of certain miRNAs in cancer can promote tumorigenesis,metastasis and invasion.Hydrogen (H2),the most abundant chemical element in the universe (constituting approximately 75% of the universes elemental mass),is seldom regarded as an important agent in medical usage,especially as a therapeutic gas.However,the role of TLR,miRNAs and Hydrogen in Radioprotection is not well studied.Here we report the novel data of TLRs,miRNAs & Hydrogen in Radioprotection.
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