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5. Pharmacokinetic Comparison of Erlotinib,Gefitinib and Icotinib in NSCLC Brain Xenograft Model

Pharmacokinetic Comparison of Erlotinib,Gefitinib and Icotinib in NSCLC Brain Xenograft Model

来源 :2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户：saintjob

【摘 要】

：

目的 we design the study aiming at detecting the pharmacokinetic difference among gefitinib,icotinib,erlotinib,and OSI-420,themain metabolite of erlotinib,in brain,CSF(cerebrospinal fluid)and plasma,bes

【作 者】

：

wenzhongchen pinghu 

【机 构】

：

Respiratory department of Xiangya hospital of CSU university

【出 处】

：

2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

【发表日期】

：

2016年4期

【关键词】

：

NSCLC erlotinib gefitinib icotinib brain metastasis pharmacokinetics 

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　　目的 we design the study aiming at detecting the pharmacokinetic difference among gefitinib,icotinib,erlotinib,and OSI-420,themain metabolite of erlotinib,in brain,CSF(cerebrospinal fluid)and plasma,besides,the preliminary efficacy of those three EGFRTKISwas assessed.

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