Study on the relationship between particle size of liposomal anticancer drug and its distribution,me

来源 :2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年 | 被引量 : 0次 | 上传用户：drake0266

【摘要】

：

【作者】

：

ZHANG Huanqing XING Jing

【机构】

：

Nanjing R&D Institute,Chia-Tai Tianqing Pharmaceutical Group Co.Ltd,Nanjing 210023,China

【出处】

：

2016年中国药物制剂大会、中国药学会药剂专业委员会2016年学术年会、中国化学制药工业协会固体制剂专业委员会2016年

【发表日期】

：

2016年4期

【关键词】

：

Liposomal anticancer drug Particle size Distribution Metabolism Tumor targeting

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　　Objective: To study the relationship between particle size of liposomal anticancer drug and its distribution,metabolism and tumor targeting.Methods:6 tumor-bearing(HT-29 cells)mice,randomly divided into three groups,fluorescence probe IR623 group(Group A),100nm liposomal anticancer drug group(Group B),and 400nm liposomal anticancer drug group(Group C).

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Study on the relationship between particle size of liposomal anticancer drug and its distribution,me

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