【摘 要】
：
Retinal ischemia-reperfusion (I/R) injury is associated with many ocular diseases.Neuronal cell death,macrophage infiltration,and oxidative injury are complications in retinal I/R injuries.Sulforaphan
【机 构】
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滨州医学院生理学教研室,山东 烟台 264003 北京大学医学部解剖与组织胚胎学系,北京 1001
【出 处】
：
中国生理学会第24届全国会员代表大会暨生理学学术大会
论文部分内容阅读
Retinal ischemia-reperfusion (I/R) injury is associated with many ocular diseases.Neuronal cell death,macrophage infiltration,and oxidative injury are complications in retinal I/R injuries.Sulforaphane (SF),an isothiocyanate found in cruciferous vegetables such as broccoli,has cytoprotective effects against oxidative stress and its effect is mediated by nuclear factor E2-related factor 2 (Nrf2),a transcription factor,and heme oxygenase-1 (HO-1),which is one of Nrf2 downstream target genes.
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