NFATC3 exerts anti-tumor and anti-viral dual function in hepatitis B virus-related hepatocellular ca

来源 :2014年APASL专题会议暨第四届乙型病毒性肝炎专题会议 | 被引量 : 0次 | 上传用户:fspdgx
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Background:The nuclear factor of activated T-cells,cytoplasmic 3(NFATC3)belongs to a family of transcription factors that can orchestrate an effective immune response mainly in T cells.But the function of NFATC3 in hepatocytes has never been addressed.Based on our previous aCGH result,deletion of NFATC3 was frequently found in hepatocellular carcinoma(HCC),thereby we aim to determine the role NFATC3 plays in hepatitis B virus(HBV)related HCC.
其他文献
Background:Protective immune response plays an important role in eliminating HBV infection.A weak immune response to HBV can lead to chronic liver disease.
会议
Background:Elevated HBV DNA levels are associated with increased risk for liver cancer and cirrhosis.Rapid and complete viral suppression correlates with lower rate of resistance development.Effective
会议
Background:CD4+T follicular helper(Tfh) cells,a new subset of immune cells,have been demonstrated to be involved in the development and prognosis of tumors.
会议
Background:The advent of nanotechnology has provided a new and powerful tool in medical fields.Of all the application of nanotechnology,nanoparticle-delivery system attracted many attentions.As a deli
会议
Background:Oobjective:To explore the influence factors on HBV relapse after Nucleos(t)ide analogues(NAs)withdrawal in the Hepatitis B e antigen positive chronic hepatitis B(CHB)patients who met NAs ce
会议
Objective:To investigate etiology,risk factors and clinical characteristics of primary hepatic carcinoma(PHC)in Hebei province to better strategies for disease prevention,diagnosis and treatment.
会议
Background:Data regarding the long term outcome of HBV-related decompensated cirrhosis is rare,especially following oral nucleos(t)ide analogues use in such patients.
会议
liver damage and is one of the major causes of fatty liver worldwide.Although many drugs have been reported to have protective effects against alcoholic liver disease(ALD),there is finite available tr
会议
Background:We amplified and analyzed the hepatitis B virus(HBV) reverse transcriptase(RT) sequences of 75 Chinese patients with chronic hepatitis B who have been treated with nucleos(t)ide analogues e
会议
Background:The aim of this study is to analysis the factors affecting HBeAg seroconversion of initial treatment using nucleoside analogue among HBeAgpositive patients.
会议