【摘 要】
：
Background:We amplified and analyzed the hepatitis B virus(HBV) reverse transcriptase(RT) sequences of 75 Chinese patients with chronic hepatitis B who have been treated with nucleos(t)ide analogues e
【机 构】
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Peking University 3rd Hospital Peking University
【出 处】
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2014年APASL专题会议暨第四届乙型病毒性肝炎专题会议
论文部分内容阅读
Background:We amplified and analyzed the hepatitis B virus(HBV) reverse transcriptase(RT) sequences of 75 Chinese patients with chronic hepatitis B who have been treated with nucleos(t)ide analogues except tenofovir,to investigate if drug resistance mutations which might
lead to tenofovir resistance such as rtA194T,rtA194T+
rtM204V+rtL180M,rtA181V/T+rtN236T,rtV214A,
rtQ215S,and the circumstance of drug resistance
mutations related to other nucleos(t)ide analogues.
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