Central role of cellular senescence in thymic stromal lymphopoietin (TSLP) induced-airway remodeling

来源 :中华医学会呼吸病学年会——2013第十四次全国呼吸病学学术会议 | 被引量 : 0次 | 上传用户:beijingmonkey
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Background Airway remodeling is a repair process occurring after airway injury and involves a wide array of pathophysiologic features, resulting in increased airway hyperres-ponsiveness in asthma.Thymic stromal lymphopoietin (TSLP), a vital cytokine, plays a critical role in orchestrating, perpetuating and amplifying the inflammatory response in asthma.TSLP is also a critical factor in airway remodeling of asthma.
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