Generation of male germ cells from mouse induced pluripotent stem cells in vitro

来源 :2012全国发育生物学大会 | 被引量 : 0次 | 上传用户：zhaojie25

【摘要】

：

　　Germ cells are the only cell type that passes genetic information to the next generation.In most metazoan species, primordial germ cells (PGCs) were induced

【作者】

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Yangfang Li Xiuxia Wang Xue Feng Shangying Liao Chunsheng Han

【机构】

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StateKeyLaboratoryofReproductiveBiology,InstituteofZoology,ChineseAcademyofSciences,Beijing100101

【出处】

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2012全国发育生物学大会

【发表日期】

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2012年10期

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论文部分内容阅读

　　Germ cells are the only cell type that passes genetic information to the next generation.In most metazoan species, primordial germ cells (PGCs) were induced from epiblasts by signals from the neighboring tissues.In vitro derivation of germ cells from the pluripotent stem cells (PSCs) such as embryonic stem cells (ESCs) and induced PSCs (iPSCs) are of great values for the treatment of infertility, for animal breeding, and for studying the mechanism of germ cell development.

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Generation of male germ cells from mouse induced pluripotent stem cells in vitro

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