【摘 要】
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The bacterium Burkholderia pseudomallei is the causative agent of melioidosis and,in endemic areas including Southeast Asia,can be isolated from moist soil and stagnant water.B.pseudomallei infects ma
【机 构】
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Department of Molecular Biology and Biotechnology,Krebs Institute,University of Sheffield,Sheffield
【出 处】
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第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会
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The bacterium Burkholderia pseudomallei is the causative agent of melioidosis and,in endemic areas including Southeast Asia,can be isolated from moist soil and stagnant water.B.pseudomallei infects many tissues,causingsubclinical infections,acute septicemia,and subacute and chronic disease.This pathogen has the ability to remain latent in a host for decades,and infections in army personnel serving in endemic areas has resulted in the pathogen being referred to by the nickname,the"Vietnam Time Bomb".There is no vaccine and the organism is multidrug resistant,complicating treatment.
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