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5. Regulation of basal and induced expression of P450s in liver cells by a transcription factor network

Regulation of basal and induced expression of P450s in liver cells by a transcription factor network

来源 :2017年第三届岭南国际DMPK论坛 | 被引量 : 0次 | 上传用户：johndovl1

【摘 要】

：

Cytochrome P450 (P450) enzymes play a critical role in metabolism of xenobiotics, including drugs and toxicants. Control of P450 expression can directly influen

【作 者】

：

Liming Chen Yifan Bao Xiao-bo Zhong 

【机 构】

：

DepartmentofPharmaceuticalSciences,SchoolofPharmacy,UniversityofConnecticut,Storrs,Connecticut,USA

【出 处】

：

2017年第三届岭南国际DMPK论坛

【发表日期】

：

2017年12期

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Cytochrome P450 (P450) enzymes play a critical role in metabolism of xenobiotics, including drugs and toxicants. Control of P450 expression can directly influence metabolism process and cause variability on drug therapeutic effects or adverse reactions.

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