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Background: Extremely elevated intracranial pressure (ICP) in Patients with HIV and cryptococcal meningitis is a poor prognostic predictor of death during initial therapy.The risks associated with implanting a cerebrospinal fluid (CSF) shunt in immunocompromised patients with ongoing CSF infection have historically discouraged surgeons from implanting CSF shunts in patients with HIV and cryptococcal meningitis.It remains unclear if ventriculoperitoneal (VP) shunts can effectively provide long-term treatment for patients with intracranial hypertension and HIV-associated cryptococcal meningitis in China.Method: The outcome of 9 patients with HIV-associated cryptococcal meningitis who were performed VP shunt for high ICP was retrospectively analyzed.The age, sex, clinical manifestations, neurological statuses, CSF features, image findings and other opportunistic infections were recorded for analysis.