【摘 要】
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Objective: We investigated the appropriate patient wait time in the supine treatment position after Intratympanic dexamethasone injection (ITDI).Methodology: In an in vivo animal study, 24 mice were i
【机 构】
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Department of Otorhinolaryngology, Keimyung University College of Medicine, Taegu Metropolitan City,
【出 处】
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The 4th East Asian Symposium on Otology(第四届东亚耳科研讨会)
论文部分内容阅读
Objective: We investigated the appropriate patient wait time in the supine treatment position after Intratympanic dexamethasone injection (ITDI).Methodology: In an in vivo animal study, 24 mice were injected intratympanically with dexamethasone.Perilymphatic fluid was sampled at 5, 10, 15, 20, 25 and 30 min post-injection.The dexamethasone concentration was analyzed using highperformance liquid chromatography.In a separate prospective clinical study, 79 patients with refractory sudden hearing loss underwent intratympanic injection.After the injection, patients remained in the supine position with the head rotated 45° to the unaffected side.Patients were divided into two groups according to the wait time in this treatment position postinjection: 30 min (n =47) and 10 min (n =32).Final hearing assessments were conducted 2 months after salvage treatment.
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