【摘 要】
：
Neurodegenerative dementias, whereof the most frequent forms are Alzheimers disease (AD) and dementia with Lewy bodies (DLB), harvest great numbers of victi
【机 构】
：
Molecular Memory Research Unit Lund University Sweden
论文部分内容阅读
Neurodegenerative dementias, whereof the most frequent forms are Alzheimers disease (AD) and dementia with Lewy bodies (DLB), harvest great numbers of victims with an alarmingly fast increase in prevalence rate worldwide.In both diseases, proteins aggregate and accumulate in the brain tissue, leading to a series of events which ultimately cause neurodegeneration and nerve cell death.In Alzheimers disease, accumulation and deposition of the amyloid-β peptide (Aβ), resulting from an imbalance between production and clearance, is considered to be the main pathological driving force (the amyloid cascade hypothesis).
其他文献
请下载后查看，本文暂不支持在线获取查看简介。
Please download to view, this article does not support online access to view profile.
为研究新疆典型淡水湖和咸水湖芦苇湿地土壤温室气体排放差异,以中国第一大内陆淡水湖博斯腾湖和新疆第一大咸水湖艾比湖为研究对象,采用静态箱-气相色谱法,利用2016年12月至
Concentric needle electromyography (EMG) has been routinely used as the primary electrodiagnostic tool for examination of neuromuscular diseases.Yet this ap
Alzheimers disease (AD) is one of the most common forms of neurodegenerative disease.Amyloid-β (Aβ) is considered as a centre molecule and plays a key rol
蝎尾蕉原产热带美洲和太平洋诸岛,主要分布在墨西哥南部、哥伦比亚、巴西、秘鲁、哥斯达里加及西印度群岛、太平洋诸岛等的雨林中。为旅人蕉科多年生草本植物,全属约40种;植
幼教事业上的男子汉──记内蒙古根河市第三幼儿园园长徐景山杜泽泉白云曾静听过他的歌声，松林曾聆听过他的教诲；大兴安岭山脚下的老阿爸、老阿妈夸他是“森林的好儿子”，天真烂
钢纤维混凝土是在普通混凝土中掺入乱向分布的短钢纤维所形成的一种新型的多相复合材料。这些乱向分布的钢纤维能够有效地阻碍混凝土内部微裂缝的扩展及宏观裂缝的形成，显著地
cherrymam@163.com问:我的孩子1个半月大,一直喝配方奶粉,最近排便越来越困难,经常哭闹,医生建议我们用药物刺激他的肛门,他才排出来。请问,孩子排便困难是怎么回事?石军大夫
Non-invasive functional imaging techniques provide essential information on anatomy and function of the brain in Amyotrophic lateral sclerosis (ALS).For the
1病例报告男,31岁。骶尾部肿痛,反复流脓5d入院。T 38℃,P 88次/min,R 18次/min,BP 120/80mm Hg。专科检查:骶尾部有一肿物大小约5cm×4cm,中央有一凹陷的窦口。临床诊断:肛