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This study was conducted to assess the effect of genetic and nongenetic factors on pre-weaning performance of crossbred lambs at Haramaya University,Ethiopia.Data of 275 Dorper sire breed x indigenous (Blackhead Ogaden [BHO] and Hararghe Highland [HH]) crossbred lambs with different blood levels of the parental breeds,collected for a 3 year period (2009 to 2011),were used in this study.