Epigenetic regulation of IL-12/IL-23 gene expression and autoimmune responses by deubiquitinase Trab

来源 :中国免疫学会第十届全国免疫学学术大会 | 被引量 : 0次 | 上传用户：zerorolove

【摘要】

：

　　Aims: The proinflammatory cytokines IL-12 and IL-23 connect innate immunity to adaptive immune responses and are also involved in autoimmune and inflammator

【作者】

：

Jin Jin Yichuan Xiao Hongbo Hu Qiang Zou Xiaoping Xie Xuhong Cheng Shao-cong Sun

【机构】

：

Life Sciences Institute,Zhejiang University,Hangzhou 310058,China

【出处】

：

中国免疫学会第十届全国免疫学学术大会

【发表日期】

：

2015年期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　Aims: The proinflammatory cytokines IL-12 and IL-23 connect innate immunity to adaptive immune responses and are also involved in autoimmune and inflammatory diseases.

其他文献

Deficiency of programmed cell death 4 attenuates atherosclerosis in hyperlipidemic mice through incr

　　Background: Programmed cell death 4 (PDCD4) is a newly defined transcriptional and translational inhibitor, and tumor suppressor.

会议

Clinical Characteristics and Genetic Profiles of Severe Combined Immunodeficiency: a Single Center E

　　Rationale: Severe combined immunodeficiency (SCID), a rare PID, is poorly characterized in China.We retrospectively reviewed patients with SCID refered to o

会议

ProfilesandChinaExperience

Il-1在红斑狼疮皮肤损伤中的作用

　　研究背景：系统性红斑狼疮(SLE)是一种严重的慢性自身免疫性疾病，其主要特征是大量自身抗体的产生和多器官的损伤，其中皮肤损伤是红斑狼疮常见的临床表现之一，但其具体的发病

会议

系统性红斑狼疮皮肤损伤自身免疫性疾病前炎性细胞因子自身抗体主要特征皮肤损害临床表现

新分子CCDC134的功能研究

　　随着基因组学和蛋白质组学的迅速发展,越来越多的新分子被发现和研究。基于此我们与国家人类基因组北方研究中心合作,采用了反向生物学策略,发现了一个能够抑制Elk1活性

会议

分子人类基因组反向生物学蛋白质组学基因组学中心抑制活性

EPSs from a Candida parapsilosis strain in the treatment of Experimental Candida Vaginitis: Exerting

　　Microbial exopolysaccharides (EPSs), long-chain polysaccharides released by a variety of organisms, have gained considerable attention for their potential i

会议

Angiotensin-converting enzyme 2 (ACE2) mediates influenza H7N9 virus-induced acute lung injury

　　Since 2013, the emergence of an avian-origin influenza A (H7N9) virus has raised concern in China.Although most infections resulted in respiratory illness,

会议

Respiratory influenza virus infection induces memory-like liver NK cells in mice

　　Aim: Although natural killer (NK) cells are classified as innate immune cells, recent studies demonstrate that NK cells can become long-lived memory cells a

会议

Raf kinase inhibitor protein and TANK-binding kinase 1 form a positive feedback loop to promote type

　　TANK-binding kinase 1 (TBK1) activation is a central event in type I interferon production in anti-virus innate immunity.However, the regulatory mechanism u

会议

NDR激酶家族在天然免疫应答中的调控作用研究进展

　　Toll样受体能够识别不同的病原相关分子模式，触发炎症反应，同时对获得性免疫反应也具有调控作用。炎症反应有助于清除入侵的病原体，但是过度或长期的炎症反应则会对机体造成

会议

激酶家族免疫应答调控作用炎症反应病原相关分子模式自身免疫性疾病Toll样受体免疫反应

Metabolic disorders trigger inflammation by reducing CD1d expression in a cell type-specific manner

会议

Epigenetic regulation of IL-12/IL-23 gene expression and autoimmune responses by deubiquitinase Trab

与本文相关的学术论文