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目的观察依达拉奉治疗急性颅脑损伤的疗效。方法将60例符合要求的急性颅脑损伤患者,随机分为依达拉奉治疗组30例和常规治疗组(对照组)30例,观察两组脑水肿面积的变化、GCS、APACHE-Ⅱ评分、疗效与预后情况。结果疗程结束后,依达拉奉治疗组和对照组在改善患者脑水肿面积、GCS、APACHE-Ⅱ评分、疗效与预后方面比较,差异均有统计学意义(P﹤0.05)。结论依达拉奉治疗急性颅脑损伤,能够明显减轻脑组织水肿,改善其神经功能缺损,提高疗效和预后。
Objective To observe the therapeutic effect of edaravone on acute craniocerebral injury. Methods Sixty patients with acute craniocerebral injury were randomly divided into edaravone treatment group (n = 30) and routine treatment group (n = 30). The changes of cerebral edema area, GCS and APACHE-Ⅱ score , Efficacy and prognosis. Results After the treatment, edaravone treatment group and control group had significant difference (P <0.05) in improving brain edema area, GCS, APACHE-Ⅱ score, curative effect and prognosis. Conclusion Edaravone treatment of acute craniocerebral injury can significantly reduce brain edema, improve their neurological deficits and improve efficacy and prognosis.