Over the last 10-15 years a range of porous polymer monoliths have successfully been applied to the high-throughput and efficient separation of proteins and large organic molecules due largely to the benefits of convective rather than diffusive mass transport.However, the same success has not been observed for the separation of small molecules, such as inorganic ions.We have recently introduced latex-coated porous polymer monoliths as anion-exchange stationary phases for capillary ion chromatography (IC) of small ions [1-3].These stationary phases were produced by coating porous poly (butyl methacrylate-co-ethylene dimethacrylateco-2-acrylamido-2-methyl-l-propanesulfonic acid) monoliths with nanometer sized quaternary ammonium functionalized latex particles, which are bound to the surface of the monolith by electrostatic binding.However, one of the main drawbacks of current monolithic formats for fast IC of small ions is the apparent lack of ion-exchange capacity.While less of an issue for the separation of large molecules such as proteins, it considerably affects the separation efficiency and sensitivity of inorganic ions, which are reliant on individual functionalities rather than spanning over an extended range of interaction sites.