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  5. Genomic characterization of a Helicobacter pylori isolate from a patient with gastric cancer in Chin

Genomic characterization of a Helicobacter pylori isolate from a patient with gastric cancer in Chin

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：hnlh007
【摘 要】
：
Background: Helicobacter pylori is well known for its relationship with the occurrence of several severe gastric diseases.The mechanisms of pathogenesis triggered by H.pylori are less well known.In th
【作 者】
：
尤元海 刘琳 张茂俊 朱远方 何利华 栗冬芳 张建中 
【机 构】
：
感染性疾病诊治协同创新中心,传染病预防控制国家重点实验室,中国疾病预防控制中心传染病预防控制所,北京,102206
【出 处】
：
第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
【发表日期】
：
2014年4期
【关键词】
：
Helicobacter pylori Gastric cancer Next generation sequencing Genomic features 
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　　Background: Helicobacter pylori is well known for its relationship with the occurrence of several severe gastric diseases.The mechanisms of pathogenesis triggered by H.pylori are less well known.In this study, we report the genome sequence and genomic characterizations of H.pylori strain HLJ039 that was isolated from a patient with gastric cancer in the Chinese province of Heilongjiang, where there is a high incidence of gastric cancer.To investigate potential genomic features that may be involved in pathogenesis of carcinoma, the genome was compared to three previously sequenced genomes in this area.
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