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  5. Construction of Histone gene mutant of Saccharomyces Cerevisiae

Construction of Histone gene mutant of Saccharomyces Cerevisiae

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：gsqj123465
【摘 要】
：
Background: Histone modification is one of the key epigenetic regulation mechanisms which plays a critical role in various biological processes.In Saccharomyces cerevisiae, the histones H3 and H4 gene
【作 者】
：
薛涛涛 郑晓东 赵秀娟 蔡禄 
【机 构】
：
数理与生物工程学院,内蒙古科技大学,包头,014010
【出 处】
：
第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会
【发表日期】
：
2014年4期
【关键词】
：
Saccharomyces cerevisiae histone modification two-step substitution 
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　　Background: Histone modification is one of the key epigenetic regulation mechanisms which plays a critical role in various biological processes.In Saccharomyces cerevisiae, the histones H3 and H4 gene are encoded by two copy, named HHT1-HHF1 and HHT2-HHF2.Specific sites of histone acetylation, methylation and other modifications have a important biological significance to eukaryotic DNA replication.
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