Enantioselective Biomimetic Total Syntheses of Kuwanons I and J, Brosimones A and B

来源 :The 24th International Society of Heterocyclic Chemistry Con | 被引量 : 0次 | 上传用户：lijingbo1985

【摘要】

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【作者】

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Jianguang Han Xia Li Xiaoguang Lei

【机构】

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College of Pharmaceutical Science and Technology,Tianjin University,Tianjin 300072,China

【出处】

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The 24th International Society of Heterocyclic Chemistry Con

【发表日期】

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2013年4期

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The asymmetric total syntheses of (-)-kuwanon I, (+)-kuwanon J, (-)-brosimone A and (-)-brosimone B were accomplished.Our strategy is based on a highly concise and biomimetic approach involving a visible light mediated regio-selective Schenck-ene reaction, as well as an asymmetric Diels-Alder cycloaddition catalyzed by chiral boron complex as key steps.

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