2. 您的位置
3. 首页
4. 会议论文
5. Synthetic Studies on Erythrina Alkaloids

Synthetic Studies on Erythrina Alkaloids

来源 :The 24th International Society of Heterocyclic Chemistry Con | 被引量 : 0次 | 上传用户：XINGQIPING

【摘 要】

：

The first asymmetric total synthesis of erythraline, one of the representative members of erythrina alkaloids, has been achieved in 17 steps and 3.6％ overall yield starting from piperonal.

【作 者】

：

Hirotatsu Umihara Tomomi Yoshino Jun Shimokawa Masato Kitamura Tohru Fukuyama 

【机 构】

：

Graduate School of Pharmaceutical Sciences,University of Tokyo,7-3-1 Hongo,Bunkyo-ku,Tokyo 113-0033,

【出 处】

：

The 24th International Society of Heterocyclic Chemistry Con

【发表日期】

：

2013年4期

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

The first asymmetric total synthesis of erythraline, one of the representative members of erythrina alkaloids, has been achieved in 17 steps and 3.6％ overall yield starting from piperonal.

其他文献

Chemoenzymatic Synthesis of Fluorinated Thomsen-Friedenreich Antigens and Their Sialylated Derivativ

Fluorine-containing T antigens were successfully synthesized using an efficient two-step one-pot two-enzyme galactosylation process and used as substrates for one-pot two-enzyme synthesis of fluorinat

会议

(p-Tol)2SO/Tf2O Promoted α-C-sialylation with N-Acetal-5-N,4-O-Oxazolidione Protected Thiosialoside

Based on preactivation protocol with (p-Tol)2SO/Tf2O,[1] a practical, straightforward, and high-yielding synthesis of α-sialyl C-glycoside was accomplished in the coupling of N-Acetal-5-N,4-O-oxazolid

会议

Highly Enantioselective Reactions Catalyzed by SPAs

Chiral cyclic phosphoric acids represent an important and widely applicable class of catalysts for a variety of enantioselective transformations.We firstly reported the chiral spirocyclic SPINOL-phosp

会议

I2-Catalyzed Intramolecular Vinylic C-S Cross-Coupling for the Synthesis of 2-Methylene-3-Thiophenon

A direct vinylic C-H thiolation is developed under metal-free conditions.Catalyzed by iodine (10 mol％), the intramolecular sp2C-S oxidative cross-coupling reaction[1] of α-alkenoyl ketene dithioacetal

会议

Design and Synthesis of Glycosyl-1,3,4-thiadiaoles

Sugar, as an energy carrier, plays a crucial role in many physiological processes, and the heterocyclic compounds possess broad anti-tumor and antiviral activities.Therefore, the investigation of the

会议

Reaction of Trithienylstibanes with Acyl Chlorides under Iron Trichloride Catalyst

Reaction of trithienylstibanes with various acyl chlorides in the presence of iron trichloride catalyst led to Friedel-Crafis type acylation at ipso-position to form acyl thiophenes in high yields.The

会议

Tandem Photo-Thermo-Photo Reaction of Dichlorocoumarin and 1,1-Diphenyl Ethylene

Highly fluorescent aromatic compounds have always been attracting organic and bioorganic chemists.They are widely used as labeling motifs in bio-imaging system.And these hetero aromatic compounds have

会议

Asymmetric Cascade Annulation via Enantioselective Oxa Diels-Alder Cycloaddition of in Situ Generate

An asymmetric cascade reaction of metallo-isochromenylium has been successfully established with multiple-bond formation viaan enantioselectiveoxa Diels-Alder reactionbycooperative catalysis of Pd(OAc

会议

Sinomenine Derivatives Embedded with Pyrazine Ring Exhibiting Potent TNF-α Inhibitory Activity

A number of sinomenine derivatives with embedment of pyrazine ring, a frequently applied drug fragment have been synthesized regioseleetively.A preliminary biological study of the regioisomeric mixtur

会议

One-step Synthesis of Indoloazocines via Gold-Catalyzed Reaction of Indole Functionality with Intern

A variety of indoloazocines can be readily prepared by 8-endo-dig cyclization of alkynylindole substrates and following rearrangement by catalysis of Ph3PAuNTf2 or other gold complexes.The reaction co

会议