OBJECTIVE To investigated the influence of parenting styles on drug use behaviors as well as psychiatric symptoms in subjects with methamphetamine use disorder (MUD).METHODS The investigation recruited 288 male patients with MUD who were under compulsory detoxification in Zhejiang Province.Questionnaires included the drug use histories, the symptoms check list(SCL-90),the Pittsburgh Sleep Quality Index (PSQI), the Egna Minnen av B(a)traffande Uppfostran-My memories of upbringing (EMBU) and the brief report of maltreatment experiences in childhood.The norm data of EMBU were from 390 high school and college students investigated in 1993.Significant correlation were determined by spearman correlation analysis.Coefficients no less than 0.3, and P<0.001 were termed as strongly significant, and correlations with P<0.05 were termed as moderately significant.RESULTS Positive reports on childhood maltreatment experiences were rare.However, subjects with MUD had more rejecting, callous, and less emotionally warm parents compared to the controls.The rearing styles were not related to the severity of drug use behaviors, including daily dosage,and the frequency of drug use.But parents emotional warmth have moderately negative relations with the methamphetamine craving (Father, c=-0.206, P<0.01 ; mother c=-0.274, P<0.001), while the punishment from mother have a positive relations with it (c=0.231, P<0.01).These relations were significant after control for drug use histories (daily dose, duration of methamphetamine use,weekly frequency of use, and frequency of binge use).Parental rejection was the main factors that related with psychological symptoms and sleep qualities.And the relationships were significant after control for drug use histories.After control for the craving, the relation of somatization and father rejection turn non-significant, but all the other correlations stood still.CONCLUSION Parenting styles have profound psychological impacts in patients with SUD.Inappropriate ways of rearing were closely related with the craving for methamphetamine and various psychological symptoms.Family treatment should become an important component in the comprehensive treatments of substance use disorders.And educations of parent-child relationship should be a crucial measure to prevent psychological and behavioral disorders in adult life.