【摘 要】
:
To investigate expression of autophagy-related proteins LC-3 and Beclin-1 in the silicosis model of rats.Ninety male SD rats were randomly divided into three groups: control group,model group and auto
【机 构】
:
School of Basic Medical Sciences, Hebei United University,Tangshan 063000
【出 处】
:
The 18th Congress of the International Federation of Associa
论文部分内容阅读
To investigate expression of autophagy-related proteins LC-3 and Beclin-1 in the silicosis model of rats.Ninety male SD rats were randomly divided into three groups: control group,model group and autophagy inhibitor (3-MA) group.The silicosis model of rats were made by one-time infusion of silica dust suspension method and given the 3-MA injection.
其他文献
Trichosanthin (TCS), a commonly used traditional Chinese medicine for early and mid-term abortion, has been found to belong to type Ⅰ ribosome-inactivating proteins.Additionally,TCS has been reported
To explore the differentiation of rat bone marrow mesenchymal stem cells (BMSCs) into cardiomyocyte-like cells, transforming growth factor beta 1(TGF-β1) and salvianolic acid B(Sal B) were used as ind
Limb bones contain structural information hidden beneath their external surface (e.g., trabecular structure, diaphyseal thickness, and cortical microstructure).These properties are plastic during life
Hippocampus is one of the neurogenesis areas in adult mammals, but the function of astrocytes in hippocampus is still less known.In our previous study, fimbria-fornix(FF) transection leads to the acti
Neural stem cells (NSCs) are pluripotent cells capable of differentiation into dopaminergic (DA) neurons, which are the major cell types damaged in Parkinsons disease (PD).
The mechanism of synaptic integration of newly generated neurons in neural stem cells (NSCs) transplantation for damaged restore function in traumatic brain injury (TBI) is not clear.In this study, BD
Oligodendrocyte development and myelination is influenced by thyroid hormones.Cell therapy using oligodendrocytes might become a promising approach for treating demyelinating disease such as multiple
To investigate the expression of the endoplasmic reticulum stress (ERS)-associated proteins GRP78, p-PERK and CHOP after TBI in rats, and determine the underlying mechanisms of 4-PBA on neuronal injur
To observe expression of LC-3 and Becline-1 in alveolar macrophages (AMs) in rat models of silicosis.The silicosis model of rats were made by one-time infusion of silica dust suspension.We performed b
The aim of present study is to investigate therapeutic potential of BMSC-conditioned medium (CM) on silicosis.Animals were exposed to silica to establish experimental model of silicosis.On the 12th ho