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5. Broad existence of pluripotency factor regulated transcript isoforms with stage-specific alternative

Broad existence of pluripotency factor regulated transcript isoforms with stage-specific alternative

来源 :第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会 | 被引量 : 0次 | 上传用户：zhouqiuhe1

【摘 要】

：

　　Transcripts with stage-specific alternative first exon (SAFE) usage involve in the regulation of many biological processes, yet their presence and functions

【作 者】

：

Guihai Feng Xiu-Jie Wang Man Tong Baolong Xia Guan-zheng Luo Meng Wang Dongfang Xie Haifeng Wan Ying Zhang Qi Zhou 

【机 构】

：

CenterforMolecularSystemsBiology,InstituteofGeneticsandDevelopmentalBiology,ChineseAcademyofSciences

【出 处】

：

第六届全国生物信息学与系统生物学学术大会暨国际生物信息学前沿研讨会

【发表日期】

：

2014年10期

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　　Transcripts with stage-specific alternative first exon (SAFE) usage involve in the regulation of many biological processes, yet their presence and functions in embryonic stem cells (ESCs) are still largely unknown.In this work, we identify 137 mESC SAFE isoforms of 128 genes expressed in both ESCs and somatic cells.

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