【摘 要】
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Purpose: To determine the relationship of cytokine/chemokine expression with the clinical presentation of hand,foot and mouth disease (HFMD).Methods: This study involved 28 mild HFMD patients,44 sever
【机 构】
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Department of Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine
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Purpose: To determine the relationship of cytokine/chemokine expression with the clinical presentation of hand,foot and mouth disease (HFMD).Methods: This study involved 28 mild HFMD patients,44 severe HFMD patients and 26 healthy children.Venous blood was tested for cytokines (IL-4,IL-12,IL-18,TNF-α,IFN-γ) and chemokines (IL-8,RANTES,MCP-1,IP-10).Stool samples from the patients were tested for EV71 nucleic acid using reverse transcription polymerase chain reaction.
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