Tropomodulin1 is involved in the regulation of water reabsorption

来源 :2016年国际生理学学术大会 | 被引量 : 0次 | 上传用户:yx065781080
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Water reabsorption in collecting duct is critical to body water homeostasis,which mainly depends on arginine vasopressin(AVP)regulated aquaporin 2(AQP2)expression and trafficking.Many evidences have showed that cytoskeletal proteins play important roles in AQP2 trafficking.Tropomodulin 1(Tmod1),the only capping protein at the pointed end of actin filament,was found expressed in the kidney.
其他文献
IGFBP2 is a pleiotrophic polypeptide that synthesized in the brain but still largely unknown its functions at neonatal brain.To unmask the function IGFBP2,acute hippocampal slices(350 μm thick)were pr
Orexins represent a recently characterized family of hypothalamic neuropeptides,which play important roles in central movement regulation.Much evidence indicates that orexin levels decrease significan
Caloric diet,such as fat and sugar,has rewarding effects.Excessive consumption of caloric food has been indicated to affect the responses to addictive substances in animal experiments.However,the poss
Objective: Circadian disturbance,including sleep disorders and behavior patterns change,are frequently seen in aging and even more pronounced in Alzheimers disease(AD).However,there is still lack of d
The aim of the present study was to investigate the changes in the firing activity of medial prefrontal cortex(mPFC)neurons at different time periods after 6-hydroxydopamine lesions of the substantia
Depression-like behavior is observed in both rats and people with hypothyroidism,which suggests that altered thyroid hormone levels are closely associated with mental illness.Furthermore,decreased ser
The hippocampus is the key structure for learning and memory in mammals,and long-term potentiation(LTP)is an important cellular mechanism responsible for learning and memory.The mammalian hippocampus
Objective: The aim of this experiment was to confirm core body temperature of UWS patients appear free-running period and become a promising dedicator of distinguishing MCS from UWS.Method: The core b
Background: Hippocampus is a key structure involved in learning and memory processes,particularly in spatial learning and memory.The mammalian hippocampus is mainly divided into the CA1,CA3,and dentat
Object: We found the therapeutic effects of Icaritin(ICT)on cerebral ischemia reperfusion injury in previous studies,but its mechanism had to be observed.MAPK Signal pathway involved in cerebral ische