Substantial variability in single-cell RNA-seq data stems from diverse sources including gene expression heterogeneity, cell cycle dynamics, and technical noise
The regulatory role of N6-methyladenosine (m6A) and its nuclear reader YTHDC1 in pre-mRNA splicing remains an enigma.Here we show that YTHDC1 promotes exon
It is well established that individual cells, even from the same origin, differ from each other in many aspects due to stochastic biological processes and diffe
Measuring gene expression in individual cells is crucial for understanding the gene regulatory network controlling human embryonic development.Here we apply
Polycomb Group (PcG) and trithorax group (trxG) proteins form multimeric protein complexes that regulate chromatin via histone modifications and modulation of n
Long non-coding RNAs (lncRNAs) are emerging as new regulators in the cancer paradigm,demonstrating potential roles in both oncogenic and tumor suppressive p