【摘 要】
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Caulis Lonicerae is an important traditional Chinese medicine used for the treatment of acute fever, headache, respiratory infection, epidemic diseases, etc.The reported active components in Caulis Lo
【机 构】
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Chromatography and Mass Spectrometry Division, Thermo Fisher Scientific 1228 Titan Way, P.O.Box 3603
【出 处】
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第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会
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Caulis Lonicerae is an important traditional Chinese medicine used for the treatment of acute fever, headache, respiratory infection, epidemic diseases, etc.The reported active components in Caulis Lonicerae are loganin, sweroside, chlorogenic acid, caffeic acid, rutin, and galuteolin, etc.Chinese Pharmacopeia 2010 regulates Caulis Lonicerae with different HPLC methods for the determination of loganin (using a phenyl stationary phase) and chlorogenic acid (using a C 18 phase), respectively.The quality control for Caulis Lonicerae, therefore, is inconvenient (i.e., two methods) and inadequate (only two target components).Besides determining loganin and chlorogenic acid, some evaluation methods for the quality control of Caulis Lonicerae use an HPLC method to determine sweroside, caffeic acid, rutin, and galuteolin, etc, on a C18 stationary phase.However, these methods require long separation times (≥ 30 min) and have insufficient peak resolution between loganin and sweroside.
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