Objective:The objective of this study is to determine whether the LNP-siRNA delivery system can be used to knock down Ihh in vivo and attenuate surgery induced OA model as a specific therapy for carti
The role of autophagy in tumor seems to be complex,with reports indicating both pro-tumor and anti-tumour roles.Here the effect of autophagy inhibition on chemosensitivity was studied in human osteosa