Angiotensin Ⅱ type 2 receptor correlates to therapeutic effects of losartan on rats with adjuvant-in

来源 :The 12th Meeting of the Asia Pacific Federation of Pharmacol | 被引量 : 0次 | 上传用户：tom95800

【摘要】

：

【作者】

：

Di WANG Yan CHANG Qing-tong WANG Wu-yi SUN Wei WEI Shan-shan HU Jie ZHU Jun YUAN Jing-jing WU Ai-wu ZHOU Yu-jing WU Won-di ZHAO Qiong HUANG

【机构】

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Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Antiinflammatory and

【出处】

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The 12th Meeting of the Asia Pacific Federation of Pharmacol

【发表日期】

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2013年4期

【关键词】

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rheumatoid arthritis adjuvant-induced arthritis losartan angiotensin Ⅱtype 2 rec

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Aim: Angiotensin Ⅱ type 1 receptor (AT1R) blocker losartan ameliorates the rheumatoid arthritis (RA) experimental model adjuvant-induced arthritis (AIA) disease progression.Angiotensin Ⅱ type 2 receptor (AT2R) mainly exerts counterregulatory actions to AT1R still remains obscure in RA.In present study, we investigated the role of AT2R in losartan-induced treatment effects on rats with AIA.

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Angiotensin Ⅱ type 2 receptor correlates to therapeutic effects of losartan on rats with adjuvant-in

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