The prospective study was designed to investigate the clinical and radiographic effects of the new functional intervertebral cervical disc prosthesis in the treatment of patients with single-level and
Bone remodeling is tightly regulated by secreted and membrane-bound factors within the bone multicellular unit (BMU).It is well established that the osteoblasts regulate osteoclast differentiation via
Previous studies have shown that novel scaffold-free self-assembled constructs can be an ideal alternative to cartilage tissue engineered based on scaffolds,which has many limitations.However,many que
Background: Since Sir John Charney in early 1960s began the orthopedic revolution in joint replacement surgery,a lot of modification and evolution has undergone in the development of suitable bearing
MicroRNAs are important gene regulators that play a profound role in tumorigenesis.MicroRNA-145 (miR-145),an important member in the family of microRNAs,is under-expressed in several types of tumors a
Background Recent advances in the design of the artificial ankle and changes in the way the operation is performed have made artificial ankle replacement a growing alternative to ankle fusion for the
Introduction: Once non-traumatic avascular necrosis of the femoral head (ANFH) happened,vascular impairment and feeble collateral circulation are followed by poor outcomes.Circulating endothelial prog