15-Lipoxygenase and 15-Hydroxyeicosatetraenoic Acid regulate intravascular thrombosis in pulmonary h

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户:Leichenglin8888
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  AIM:Pulmonary arterial hypertension (PAH) is a disease characterized by thickening of pulmonary artery walls,elevated pulmonary vascular resistance,pulmonary vascular thrombotic lesions and right-heart failure.15-lipoxygenase (15-LO) /15-hydroxyeicosatetraenoic acid (15-HETE) was an important mediator in the regulation of hypoxic pulmonary hypertension,including the pulmonary vasoconstriction and remodeling.
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